Inter Miami made little headway in their unlikely bid to make the playoffs as they were held scoreless for the first time in the 10 games of the Messi era.
The Argentine star had scored 11 goals in nine appearances since joining Inter Miami — including their run to the Leagues Cup crown, in a US Open Cup semi-final and in his regular-season debut off the bench in New York on Saturday.
The workload may have finally caught up with him on Wednesday as he was unable to work the magic again in front of another star-studded crowd at a blustery DRV PNK Stadium, where boxing great Floyd Mayweather and FIFA chief Gianni Infantino were among the spectators.