Wembanyama had 28 points and 12 rebounds, Devin Vassell also scored 28 points and the Spurs beat the Oklahoma City Thunder 132-118 on Thursday night.
Wembanyama added seven assists, five blocks and two assists while shooting 9 for 17 from the field and 5 for 7 on 3-pointers while playing the entire fourth quarter.
He is the first player in NBA history with 10 rebounds, five assists, five blocks, and five 3-pointers in a game.