The San Francisco 49ers ruled out the All-Pro running back Christian McCaffrey for Week 2 against the Minnesota Vikings due to calf and Achilles injuries, the team announced Friday.
McCaffrey was a surprise inactive in Week 1 after originally saying he expected to play. Head coach Kyle Shanahan said after the 49ers’ win Monday that the injuries were bothering the 2023 Offensive Player of the Year “a little too much.”