The Dallas Cowboys travel to Charlotte to face the Carolina Panthers in a key NFC matchup at Bank of America Stadium. With both teams hovering around .500, this game could prove pivotal for early playoff positioning. Here’s everything you need to know about how to watch, betting odds, injuries, and key stats.
Game Information
- Matchup: Dallas Cowboys (2-2-1) vs. Carolina Panthers (2-3)
- Date/Time: Sunday, October 12, 2025 – 1:00 PM ET
- Venue: Bank of America Stadium, Charlotte, NC
- TV Broadcast: FOX
- Weather Forecast: 68°F, clear skies (via AccuWeather)
Cowboys vs. Panthers Odds (via ESPN BET)
- Spread: Cowboys -3.5 (-105), Panthers +3.5 (-120)
- Total Points: 49.5
- Over 49.5: -105
- Under 49.5: -115
- Moneyline: Cowboys -185, Panthers +155
Dallas enters as a slight favorite on the road, but the betting line suggests a competitive contest.
Cowboys vs. Panthers Betting Trends
- Cowboys are 8-4 ATS in their last 12 games.
- The OVER is 9-4 in Dallas’ last 13 games.
- Cowboys are 12-3 straight up in their last 15 games vs. Panthers.
- Dallas is 8-3 ATS in their last 11 games vs. NFC South opponents.
- Panthers are 10-4 ATS in their last 14 games.
- The OVER is 7-2 in Carolina’s last 9 games.
- Panthers are 7-1 ATS in their last 8 games overall.
- Carolina is 1-9 straight up in their last 10 games vs. NFC East opponents.
Cowboys vs. Panthers Injury Report
Dallas Cowboys
- Jalen Brooks, WR – Questionable
- KaVontae Turpin, WR – Questionable
- CeeDee Lamb, WR – Questionable
- Tyler Guyton, OT – Questionable
- Tyler Booker, G – Out
Carolina Panthers
- Tershawn Wharton, DT – Questionable
- Chau Smith-Wade, CB – Questionable
- Ja’Tavion Sanders, TE – Questionable
- Chuba Hubbard, RB – Questionable
- Jalen Coker, WR – IR
Wide receiver injuries could impact Dallas’ passing attack, while Carolina’s backfield depth may be tested with Hubbard questionable.
Season Leaders
Dallas Cowboys
- Passing: Dak Prescott – 1,356 yards, 10 TDs, 3 INTs
- Rushing: J. Williams – 447 yards, 5 TDs
- Receiving: George Pickens – 357 yards, 5 TDs
Carolina Panthers
- Passing: Bryce Young – 951 yards, 7 TDs, 4 INTs
- Rushing: Rico Dowdle – 289 yards, 2 TDs
- Receiving: Tetairoa McMillan – 351 yards, 2 TDs
Prescott has been efficient to start the season, while Bryce Young continues to show flashes of growth for Carolina.
Key Storylines to Watch
- Cowboys’ Wide Receiver Depth: If CeeDee Lamb can’t go, Dallas will rely heavily on George Pickens and depth targets.
- Bryce Young’s Development: The Panthers QB faces a tough Cowboys defense but has a growing connection with T. McMillan.
- Running Back Duel: J. Williams has been a red-zone machine for Dallas, while Rico Dowdle anchors Carolina’s rushing attack.
Prediction
Dallas’ defense and Dak Prescott’s efficiency give them an edge, but Carolina’s strong ATS record suggests they’ll keep this one close. Expect a tight game with the Cowboys narrowly covering the spread.
Final Word
Catch the Dallas Cowboys vs. Carolina Panthers live from Bank of America Stadium on FOX at 1:00 PM ET, Sunday, October 12, 2025. With both teams looking to stay in the playoff hunt, this NFC clash is one of the most intriguing matchups of Week 6.