The San Francisco 49ers (5-2) hit the road to face the Houston Texans (2-4) in an interconference matchup on Sunday, October 26, 2025, at NRG Stadium in Houston, Texas. Kickoff is set for 1:00 p.m. ET (12:00 p.m. CT) on FOX.
The 49ers enter Week 8 as one of the NFC’s most complete teams, while the Texans aim to pull off an upset behind C.J. Stroud at home.
Game Information
- Matchup: San Francisco 49ers (5-2) vs. Houston Texans (2-4)
- Date: Sunday, October 26, 2025
- Kickoff: 1:00 p.m. ET / 12:00 p.m. CT
- Venue: NRG Stadium, Houston, TX
- Weather: 79°F and sunny (AccuWeather)
- TV Channel: FOX
- Streaming: Watch live via Fubo, Hulu + Live TV, YouTube TV, Sling TV, or the FOX Sports App.
How to Watch 49ers vs. Texans Live
On TV:
The game will be televised regionally on FOX, with kickoff at 1:00 p.m. ET.
Streaming Options:
Fans can stream the game through several live-TV services carrying FOX, including:
- Fubo (offers a free trial and local FOX coverage)
- Hulu + Live TV and YouTube TV (both include FOX nationwide)
- Sling TV Blue Package (for markets with FOX affiliates)
- FOX Sports App (with TV provider login)
In Person:
Tickets for the game are available through StubHub and Ticketmaster for fans attending at NRG Stadium.
Betting Odds (via ESPN BET Sportsbook)
| Bet Type | 49ers | Texans |
|---|---|---|
| Spread | -1.5 (EVEN) | +1.5 (-120) |
| Moneyline | -115 | -105 |
| Total (O/U) | 42.5 points | |
| Over Odds | -105 | Under Odds -115 |
Odds as of October 21; subject to change.
The 49ers enter as slight road favorites, reflecting a tight matchup between two strong quarterbacks and defensive fronts.
Team Leaders
| Category | 49ers | Texans |
|---|---|---|
| Passing Yards | M. Jones – 1,404 yds (6 TD, 4 INT) | C.J. Stroud – 1,305 yds (9 TD, 4 INT) |
| Rushing Yards | C. McCaffrey – 465 yds (3 TD) | N. Chubb – 265 yds (2 TD) |
| Receiving Yards | C. McCaffrey – 516 yds (3 TD) | N. Collins – 339 yds (3 TD) |
| Sacks Leader | B. Huff – 4 | D. Hunter – 4 |
Game Preview
The 49ers enter this matchup as one of the NFC’s top contenders with a balanced offense and stout defense. Christian McCaffrey remains a dual-threat weapon for San Francisco, leading the team in both rushing and receiving yards.
For Houston, C.J. Stroud continues to show poise in his second season, and the Texans will look to use their speed at wide receiver to stretch San Francisco’s secondary. With both defenses capable of creating pressure, expect a low-scoring, physical contest at NRG Stadium.