The Buffalo Bills will travel to Atlanta for a Monday Night Football clash with the Falcons in Week 6. Both teams have playoff ambitions, and this primetime showdown at Mercedes-Benz Stadium could set the tone for the rest of their seasons.
Game Information
- Matchup: Buffalo Bills (4-1) vs. Atlanta Falcons (2-2)
- Date/Time: Monday, October 13, 2025 – 7:15 PM ET
- Venue: Mercedes-Benz Stadium, Atlanta, GA
- Weather Forecast: 73°F, clear skies (via AccuWeather)
- TV Broadcast: ESPN
Buffalo vs. Atlanta Odds (via ESPN BET)
- Opening Line: Buffalo -4.5, Atlanta +4.5
- Current Spread: Bills -3.5 (-120), Falcons +3.5 (EVEN)
- Total Points: 48.5
- Over 48.5: -105
- Under 48.5: -115
- Moneyline: Bills -200, Falcons +170
Buffalo enters as the road favorite, but Atlanta has been tough at home and could make this a closer contest than expected.
Season Leaders
Buffalo Bills
- Passing: Josh Allen – 1,217 yards, 9 TDs, 2 INTs
- Rushing: James Cook – 450 yards, 5 TDs
- Receiving: Dalton Kincaid – 287 yards, 3 TDs
Atlanta Falcons
- Passing: Michael Penix Jr. – 918 yards, 3 TDs, 3 INTs
- Rushing: Bijan Robinson – 314 yards, 1 TD
- Receiving: Bijan Robinson – 270 yards, 1 TD
Buffalo continues to thrive behind Josh Allen’s dual-threat ability, while James Cook has been dominant on the ground. For Atlanta, rookie QB Michael Penix Jr. is finding his footing, but star running back Bijan Robinson remains the centerpiece of their offense both rushing and receiving.
Key Storylines to Watch
- Allen vs. Falcons Defense: Josh Allen’s efficiency through the air will be tested against an Atlanta defense that has improved in coverage.
- Bijan Robinson’s Impact: Robinson has carried the Falcons’ offense with over 580 scrimmage yards through four games. Atlanta’s ability to use him as both a runner and receiver will be critical.
- Rookie Spotlight: Michael Penix Jr. faces one of the NFL’s toughest defenses in prime time, and how he performs could define the game.
Prediction
The Bills enter this game with more offensive firepower and a defense capable of making Penix Jr.’s night difficult. Atlanta will rely heavily on Bijan Robinson to control tempo, but Buffalo’s balance makes them a strong pick to cover the spread.
Final Word
Tune in on ESPN at 7:15 PM ET, Monday, October 13, 2025 as the Buffalo Bills take on the Atlanta Falcons at Mercedes-Benz Stadium. With Josh Allen leading the charge and Atlanta looking to pull off a statement win, this Monday Night Football matchup promises plenty of drama.