NFL Week 2 kicks off tonight with Thursday Night Football as the Detroit Lions travel to Buffalo to face the Bills on Thursday, September 17, 2026.
There is only one NFL game scheduled for today, giving football fans a standalone matchup in prime time.
NFL Games Today – September 17, 2026
Detroit Lions at Buffalo Bills
Date: Thursday, September 17, 2026
Kickoff Time: 8:15 PM ET
Location: Highmark Stadium, Orchard Park, New York
TV/Streaming: Prime Video
Game: Thursday Night Football
The Lions and Bills enter the Thursday night matchup looking to build momentum early in the 2026 NFL regular season.
What Time Is the NFL Game Tonight?
The Detroit Lions vs. Buffalo Bills game is scheduled to kick off at 8:15 PM ET on Thursday night.
For viewers in other U.S. time zones, kickoff is scheduled for 7:15 PM CT, 6:15 PM MT and 5:15 PM PT.
What Channel Is Lions vs. Bills On?
Thursday Night Football between the Lions and Bills will stream nationally on Prime Video.
Fans will need access to Prime Video to watch the national broadcast of the game, subject to applicable local-market broadcast arrangements.
Lions vs. Bills Thursday Night Football
Detroit at Buffalo provides an intriguing opening matchup for NFL Week 2.
Both teams have postseason aspirations, and an early-season Thursday night game provides an opportunity to pick up an important win before the rest of the NFL schedule gets underway Sunday.
The game also puts two of the league’s prominent offenses on the national stage in one of Week 2’s marquee matchups.
NFL Week 2 Starts Tonight
Lions vs. Bills is the only NFL game scheduled for Thursday, September 17.
After Thursday Night Football, the Week 2 schedule continues with a full slate of games on Sunday, September 20, followed by Monday Night Football on September 21.
NFL Games Today: Quick Summary
NFL fans have one game to watch today: Detroit Lions at Buffalo Bills.
Kickoff is scheduled for 8:15 PM ET on Thursday, September 17, 2026, from Highmark Stadium in Orchard Park, with the game available nationally on Prime Video.
For anyone searching for NFL games today, NFL schedule today, NFL games tonight, Thursday Night Football tonight, Lions vs. Bills time, or what channel the NFL game is on today, Detroit vs. Buffalo is the lone NFL matchup on the schedule.