The San Francisco 49ers are underway in the 2026 NFL season, with a schedule that features NFC West rivalry games, international matchups and several high-profile opponents.
San Francisco opened the season with back-to-back victories and enters Week 3 with a 2-0 record. The 49ers will look to continue their strong start when they face the Arizona Cardinals on Sunday, September 27.
San Francisco 49ers 2026 Schedule
All kickoff times below are listed in Eastern Time.
| Week | Date | Matchup | Time/Result |
|---|---|---|---|
| Week 1 | Thursday, Sept. 10 | 49ers vs. Rams in Melbourne | W, 27-7 |
| Week 2 | Sunday, Sept. 20 | Dolphins at 49ers | W, 35-13 |
| Week 3 | Sunday, Sept. 27 | Cardinals at 49ers | 4:05 p.m. ET |
| Week 4 | Sunday, Oct. 4 | Broncos at 49ers | 4:25 p.m. ET |
| Week 5 | Sunday, Oct. 11 | 49ers at Seahawks | 4:25 p.m. ET |
| Week 6 | Monday, Oct. 19 | Commanders at 49ers | 8:15 p.m. ET |
| Week 7 | Sunday, Oct. 25 | 49ers at Falcons | 1:00 p.m. ET |
| Week 8 | Sunday, Nov. 1 | BYE | — |
| Week 9 | Sunday, Nov. 8 | Raiders at 49ers | 4:05 p.m. ET |
| Week 10 | Sunday, Nov. 15 | 49ers at Cowboys | 4:25 p.m. ET |
| Week 11 | Sunday, Nov. 22 | Vikings vs. 49ers in Mexico City | 8:20 p.m. ET |
| Week 12 | Sunday, Nov. 29 | Seahawks at 49ers | 4:25 p.m. ET |
| Week 13 | Sunday, Dec. 6 | 49ers at Giants | 1:00 p.m. ET |
| Week 14 | Sunday, Dec. 13 | Rams at 49ers | 4:25 p.m. ET |
| Week 15 | Thursday, Dec. 17 | 49ers at Chargers | 8:15 p.m. ET |
| Week 16 | Sunday, Dec. 27 | 49ers at Chiefs | 4:25 p.m. ET |
| Week 17 | Sunday, Jan. 3 | Eagles at 49ers | 8:20 p.m. ET |
| Week 18 | Jan. 9 or 10 | 49ers at Cardinals | TBD |
What Is the 49ers’ Next Game?
The San Francisco 49ers’ next game is against the Arizona Cardinals on Sunday, September 27, 2026.
Kickoff is scheduled for 4:05 p.m. ET.
The matchup will be an important early NFC West game for San Francisco as the 49ers attempt to build on their 2-0 start.
49ers International Games in 2026
San Francisco has two notable international appearances on its 2026 schedule.
The 49ers opened the season against the Los Angeles Rams in Melbourne, Australia, winning 27-7.
San Francisco is also scheduled to face the Minnesota Vikings in Mexico City on Sunday, November 22. That game is scheduled for 8:20 p.m. ET.
When Is the 49ers Bye Week?
The 49ers have their bye during Week 8.
San Francisco will be off on the weekend of November 1 before returning to action against the Las Vegas Raiders on November 8.
Key Games on the 49ers Schedule
The NFC West schedule remains especially important, with San Francisco facing the Seattle Seahawks twice, Arizona Cardinals twice and Los Angeles Rams twice.
Other notable games include a road matchup against the Kansas City Chiefs on December 27 and a home game against the Philadelphia Eagles on January 3.
The 49ers will also renew their Bay Area rivalry with the Las Vegas Raiders on November 8.
Where to Watch San Francisco 49ers Games in 2026
49ers games throughout the season can air across CBS, FOX, NBC, ESPN/ABC, Prime Video and other NFL broadcast partners depending on the matchup.
Nationally televised games may also be available through the corresponding streaming services, while NFL Sunday Ticket provides access to eligible out-of-market Sunday afternoon games.
Fans should check the television listing for each individual matchup because NFL broadcast assignments and flex scheduling can change during the season.
49ers 2026 Schedule Outlook
San Francisco’s 2026 schedule features international travel, six NFC West games and several matchups against recent playoff contenders.
After beginning the season 2-0, the 49ers now turn their attention to Arizona before facing Denver and Seattle in the following two weeks.
The second half of the schedule includes games against the Cowboys, Vikings, Seahawks, Rams, Chiefs and Eagles before San Francisco finishes the regular season on the road against the Cardinals.
The Week 18 kickoff date and time will be announced later by the NFL.
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