The San Francisco 49ers and Washington Commanders face off on Monday Night Football on October 19, 2026, in Week 6 of the NFL season. Both teams enter the matchup with important questions surrounding their wide receiver depth charts, including injuries and the availability of key offensive playmakers.
San Francisco will be without Deebo Samuel Sr. and Christian Kirk, while Washington receives a boost with Stefon Diggs available after dealing with a hamstring injury.
Here is a look at the 49ers vs. Commanders wide receiver depth charts, injury updates and available players for Monday Night Football.
San Francisco 49ers WR Depth Chart Today vs. Commanders
The 49ers enter Monday night’s matchup with Mike Evans leading their receiving corps. However, injuries have forced San Francisco to rely on additional depth at the position.
| Depth Chart | Wide Receiver | Game Status |
|---|---|---|
| WR1 | Mike Evans | Active |
| WR2 | Brandin Cooks | Active |
| WR3 | Jacob Cowing | Active |
| WR4 | Jordan Watkins | Active |
| Depth | Malik Turner | Active |
| Injured | Deebo Samuel Sr. | Out (Hamstring) |
| Injured | Christian Kirk | Out (Calf) |
Who Is the 49ers’ No. 1 Wide Receiver Tonight?
Mike Evans is San Francisco’s top available wide receiver against Washington.
Despite dealing with rib and Achilles concerns, Evans is available for Monday Night Football and figures to play an important role in the 49ers’ passing attack.
Brandin Cooks provides veteran experience, while Jacob Cowing and Jordan Watkins offer additional receiving options.
Malik Turner was also elevated from the practice squad to provide depth.
Why Isn’t Deebo Samuel Playing Tonight?
Deebo Samuel Sr. is unavailable for the 49ers’ Week 6 matchup against the Commanders because of a hamstring injury.
His absence leaves San Francisco without one of its versatile offensive weapons and could create additional opportunities for other receivers.
Christian Kirk is also sidelined with a calf injury, further limiting the 49ers’ available receiving options.
Washington Commanders WR Depth Chart Today vs. 49ers
Washington enters Monday Night Football with Terry McLaurin and Stefon Diggs leading its wide receiver group.
The Commanders’ Week 6 depth chart features a combination of established veterans and younger receivers.
| Depth Chart Position | Starter | Backup |
|---|---|---|
| WR1 | Terry McLaurin | Treylon Burks |
| WR2 | Stefon Diggs | Luke McCaffrey |
| WR3 | Dyami Brown | Antonio Williams |
Who Is the Commanders’ No. 1 Wide Receiver Tonight?
Terry McLaurin remains one of Washington’s primary receiving weapons heading into Monday Night Football.
McLaurin brings experience and reliable route-running ability to the Commanders’ passing offense.
Stefon Diggs gives Washington another established receiver capable of making plays against San Francisco’s secondary.
Dyami Brown provides another receiving option, while Treylon Burks, Luke McCaffrey and Antonio Williams add depth.
Is Stefon Diggs Playing Tonight vs. 49ers?
Yes. Stefon Diggs is active for the Commanders against the 49ers in Week 6.
Diggs missed Washington’s previous game because of a hamstring injury but is available for Monday Night Football.
His return gives Washington another experienced target alongside Terry McLaurin.
49ers vs. Commanders WR Injury Report for Week 6
Several receivers have dealt with injuries heading into Monday’s matchup.
| Player | Team | Injury | Status |
|---|---|---|---|
| Mike Evans | 49ers | Ribs/Achilles | Active |
| Deebo Samuel Sr. | 49ers | Hamstring | Out |
| Christian Kirk | 49ers | Calf | Out |
| Stefon Diggs | Commanders | Hamstring | Active |
The biggest concern for San Francisco is the absence of Samuel and Kirk, which reduces the team’s established receiving options.
Washington, meanwhile, benefits from having Diggs available alongside McLaurin.
Which Team Has the Better WR Depth Chart Tonight?
On paper, Washington appears to have an advantage in experienced receiving options entering Monday Night Football.
The Commanders have Terry McLaurin and Stefon Diggs available, giving their passing offense two established veterans.
San Francisco still has Mike Evans and Brandin Cooks, but injuries to Samuel and Kirk could place additional responsibility on Jacob Cowing, Jordan Watkins and other depth receivers.
However, actual production will depend on quarterback play, offensive schemes, defensive matchups and how each team distributes targets.
Where to Watch 49ers vs. Commanders Monday Night Football
Here are the game details for the Week 6 matchup.
- Matchup: Washington Commanders vs. San Francisco 49ers
- Date: Monday, October 19, 2026
- Kickoff: 8:15 p.m. ET / 5:15 p.m. PT
- Location: Levi’s Stadium, Santa Clara, California
- Game: Monday Night Football, NFL Week 6
Fans should check their local television listings and streaming provider for broadcast availability.
Final Thoughts: 49ers vs. Commanders Wide Receivers Tonight
The 49ers and Commanders enter Monday Night Football with different situations at wide receiver.
San Francisco will rely heavily on Mike Evans and Brandin Cooks while managing the absences of Deebo Samuel Sr. and Christian Kirk.
Washington enters with Terry McLaurin and Stefon Diggs available, potentially giving the Commanders an advantage in experienced receiving talent.
The performance of both teams’ wide receiver groups could play a significant role in determining the outcome of this Week 6 matchup.
Note: Depth chart positions reflect the pregame information provided and do not guarantee starting formations, snap counts or targets.