Adam Schefter reported that San Francisco 49ers wide receivers Mike Evans and Deebo Samuel have both been ruled out for Sunday’s Week 7 road game against the Atlanta Falcons. Evans is sidelined with an Achilles issue, while Samuel is dealing with a hamstring injury. The dual absences create a significant challenge for a 49ers receiving corps already managing depth concerns this season.
Injury Details for Evans and Samuel
Mike Evans, who signed with the 49ers in free agency in 2026 after a long tenure with the Tampa Bay Buccaneers, has been a reliable veteran presence in the offense. His Achilles problem keeps him out of the Falcons matchup. Deebo Samuel’s hamstring injury adds another layer of difficulty, as the versatile wideout has been a key piece alongside Evans for quarterback Brock Purdy.
These updates come as the 49ers prepare for a road contest in Atlanta, where offensive consistency has been tested by earlier injuries throughout the season.
How the Absences Affect the 49ers Offense
Losing both Evans and Samuel removes two experienced options from Purdy’s arsenal. Evans brought veteran route-running and red-zone reliability after his Buccaneers years, while Samuel’s ability to create after the catch and contribute in multiple roles made him a unique weapon. With both unavailable, the 49ers must redistribute targets across a thinner group of pass-catchers.
The offense was already navigating prior injuries, so this Week 7 development increases the pressure on the remaining receivers and the running game to generate production. Expect the coaching staff to lean on shorter, high-percentage throws and creative personnel packages to keep the unit functional against the Falcons.
Elevated Roles for Other 49ers Receivers
With Evans and Samuel sidelined, opportunities open for other players on the roster. Christian Kirk, Brandin Cooks, and Jordan Watkins are among those likely to see increased snaps and targets. Kirk offers a steady intermediate option, Cooks brings veteran experience on the outside, and Watkins can provide speed and depth.
These players will need to step up in both the starting lineup and rotational roles. The 49ers may also involve tight ends and running backs more heavily in the passing game to offset the loss of two primary wideouts. Fantasy managers and bettors should monitor the official inactives list closer to kickoff for final confirmation.
Broader Context for the 49ers-Falcons Matchup
The 49ers enter this road game looking to maintain offensive rhythm despite the depleted wide receiver room. Atlanta’s defense will look to capitalize on the absences by focusing on limiting the remaining skill-position players. On the other side, San Francisco’s defense and special teams will need to keep the game manageable.
For fans tracking the 49ers’ season trajectory, this injury news highlights ongoing depth questions at wide receiver. How the team adjusts on Sunday could influence both short-term results and longer-term planning around the position.
Looking Ahead
Mike Evans and Deebo Samuel being ruled out for the Atlanta Falcons game forces immediate adjustments for the 49ers. While the team has shown resilience with a varied offensive approach under Brock Purdy, the loss of two key receivers in Week 7 tests the depth of the group. Expect Kirk, Cooks, and Watkins to shoulder larger roles as San Francisco works through the matchup.
Check official team injury reports and Schefter’s updates for any last-minute changes before kickoff.