Los Angeles Rams running back Kyren Williams is expected to play against the San Francisco 49ers today as the NFC West rivals open the 2026 NFL regular season in Melbourne, Australia.
Williams does not carry an injury designation entering the game and is not listed among the Rams players dealing with an injury that could affect his Week 1 availability.
So, is Kyren Williams playing today against the 49ers?
Yes. Williams is expected to play and should be available for his normal role in the Rams backfield against San Francisco.
Is Kyren Williams Playing Today?
Kyren Williams is expected to play today for the Rams against the 49ers.
Williams does not appear on Los Angeles’ final Week 1 injury report.
The Rams listed several players during the week, but defensive lineman Aaron Donald was the only Los Angeles player given an out designation.
Barring an unexpected issue before kickoff, Williams should be active for the season opener.
The official inactive list released before the game will provide final confirmation.
Is Kyren Williams Injured?
There is currently no reported injury expected to prevent Williams from playing against San Francisco.
Williams was not included on the Rams’ final injury report for the game.
That is particularly encouraging for Los Angeles because Williams enters another season as one of the key pieces of Sean McVay’s offense.
With no injury designation attached to Williams, there is no current indication that his workload needs to be restricted because of an injury.
Kyren Williams Week 1 Status vs. 49ers
Here is Williams’ status entering the Rams’ season opener:
| Kyren Williams Week 1 Status | Details |
|---|---|
| Player | Kyren Williams |
| Team | Los Angeles Rams |
| Position | Running Back |
| Opponent | San Francisco 49ers |
| Week | Week 1 |
| Date | Thursday, September 10, 2026 |
| Injury Designation | None |
| Expected Status | Playing |
The official inactive list remains the final confirmation, but Williams is currently on track to play.
Will Kyren Williams Start Against the 49ers?
Williams is expected to be one of the Rams’ primary running backs against San Francisco.
Los Angeles enters the season with Williams, Blake Corum and Ronnie Rivers on its initial 53-man roster at running back.
Williams remains an important part of the Rams’ rushing attack, although Corum gives Los Angeles another established option in the backfield.
How Sean McVay divides carries between Williams and Corum will be something to watch during the season opener.
Will Kyren Williams Be on a Snap Count?
There has been no indication that Williams will be placed on a snap count because of an injury.
However, that does not necessarily mean Williams will receive every available running-back opportunity.
The Rams have Blake Corum available, giving the coaching staff flexibility to rotate its running backs and manage Williams’ workload over the course of the season.
The Week 1 matchup should provide an early indication of how Los Angeles plans to divide its backfield touches in 2026.
Rams Running Back Depth Chart
Los Angeles entered the regular season with three running backs on its initial 53-man roster:
| RB | Player |
|---|---|
| 1 | Kyren Williams |
| 2 | Blake Corum |
| 3 | Ronnie Rivers |
Williams and Corum give Los Angeles an experienced combination at the top of the depth chart.
Williams enters 2026 looking to continue a run of productive seasons in Sean McVay’s offense, while Corum is coming off a 2025 season in which he recorded 145 carries for 746 rushing yards and six touchdowns.
Why Kyren Williams Playing Matters for the Rams
Having Williams available gives Matthew Stafford and the Rams another important weapon against San Francisco.
Williams’ ability to produce on the ground can help Los Angeles establish offensive balance rather than relying entirely on Stafford and the passing game.
He can also contribute as a receiver and in pass protection, making him valuable beyond his rushing attempts.
Against a division opponent like San Francisco, maintaining that versatility could be especially important.
Kyren Williams vs. 49ers
Williams’ workload will be one of the more interesting offensive storylines in the Rams’ season opener.
San Francisco enters the game with several important defensive players available, including Nick Bosa.
That could make establishing the running game challenging for Los Angeles.
Williams and Corum could both receive opportunities as the Rams attempt to keep San Francisco’s defense from focusing exclusively on Stafford and the passing attack.
What Time Is Rams vs. 49ers Today?
The Los Angeles Rams and San Francisco 49ers play Thursday, September 10, 2026, at the Melbourne Cricket Ground in Melbourne, Australia.
Kickoff is scheduled for 8:35 p.m. ET / 5:35 p.m. PT.
Because of the time difference, the game takes place Friday morning in Melbourne.
The matchup is the first regular-season NFL game played in Australia.
Rams vs. 49ers Week 1 Game Information
| Game Information | Details |
|---|---|
| Matchup | San Francisco 49ers vs. Los Angeles Rams |
| Week | Week 1 |
| Date | Thursday, September 10, 2026 |
| Kickoff | 8:35 p.m. ET |
| Location | Melbourne, Australia |
| Stadium | Melbourne Cricket Ground |
| Rams RB | Kyren Williams |
| Williams Status | Expected to play |
Is Kyren Williams Playing Today? Final Update
Yes, Kyren Williams is expected to play for the Los Angeles Rams against the San Francisco 49ers in Week 1.
Williams does not carry an injury designation and is not listed on the Rams’ final injury report.
Unless something unexpected occurs before kickoff, Williams should be active and available for Los Angeles.
The biggest question is therefore not whether Williams will play, but how the Rams divide their running-back workload between Williams and Blake Corum in their first game of the 2026 season.